DNA
Part:BBa_K5310022:Design
Designed by: Elias Pilianidis Group: iGEM24_thessaloniki (2024-09-26)
T3 hairpin arm
Assembly Compatibility:
- 10INCOMPATIBLE WITH RFC[10]Illegal EcoRI site found at 17
- 12INCOMPATIBLE WITH RFC[12]Illegal EcoRI site found at 17
- 21INCOMPATIBLE WITH RFC[21]Illegal EcoRI site found at 17
- 23INCOMPATIBLE WITH RFC[23]Illegal EcoRI site found at 17
- 25INCOMPATIBLE WITH RFC[25]Illegal EcoRI site found at 17
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
Designed by our team based on complementarity with the rest of the Y hairpin, the H1 arm of the HCR hairpin as well as stability standards (thermodynamics, closing base pairs, loop size).
Source
The structure may not be as stable in vivo as it is shown to be in NUPACK and in vitro experiments.